Cancer prevention with GCP Genikinoko
Q: Can GCP Genikinoko by QOL be used for prevention of cancer if I go on bio-identical hormones?
A: GCP Genikinoko is for cancer cells of the prostate, ovaries and breast. Here is a little more info on this product:
Genistein Combined Polysaccharide (GCP) is a fermented soy genistein concentrate plus contains a medicinal mushroom complex for the immune system. GCP is organically produced and is not a GMO crop (Genetically Modified Organism) most genistein is from GMO soy. GCP has been compared to genistein products, and research has shown that GCP is far superior and more effective than genistein alone.
In-vivo trials by Dr. Aaron Katz confirm that GCP is far superior than Genistein for cancer cell apoptosis. Genistein is a very good substance for a prostate cancer patient, but GCP is superior in the following ways:
1) Pure Genistein is very expensive and hard to find.
2) GCP contains many other active components such as daizein, and glycitein in addition to Genistein, which enhance Genistein’s function.
3) Commercial Genistein found in soy products is not fermented which causes leaching of critical nutrients from the GI during regular consumption.
4) Most soy products are GMO (Genetically Modified Organisms) which have not been tested for long term safety in humans and have been found to cause genetic mutations in animals. These GMO foods have unseen dangers not found in GCP. Most importantly, GCP is far superior to Genistein since it also contains polysaccharide from Reishi mushrooms shown to have powerful effect on nourishing the immune system.
We usually sell this to those with hormone-sensitive cancers. I think it could be used for prevention and if you are interested, I could contact the company and find out more specifics on using this as a preventive.
Regarding taking soy isoflavones which are not fermented, the research is a bit theoretical at this point, but there is thought that the phytoestrogens in soy isoflavones can put one at higher risk for hormone-sensitive cancers if there are genetic risks or a past history of uterine, ovarian, breast and endometrial cancers. The research evidence on this is not in at this time, so it is more or less a warning to those who are at high risk for these kinds of cancer. However, I did read a recent paper which looked at many studies on soy consumption with those who have had breast cancer, and they found that a moderate soy consumption seem to be protective against a re-occurrence of developing cancer again.
There is controversy about the role of soy in breast cancer. Population studies suggest that soy is protective against breast cancer when eaten in moderation. Asian women who eat a traditional Asian diet with several servings of soy a week seem to have a lower risk of developing breast cancer. However, some researchers suggest that, due to the estrogenic effects of soy, it might increase the risk of breast cancer if eaten in large quantities. Preliminary research suggests that soy stimulates proliferation of normal human breast tissue. More research is needed to define the role of soy in breast cancer.
There is also some evidence that suggests women who take a concentrated soy isoflavone extract providing 120 mg/day of isoflavones do not have endometrial thickening after 6 months of treatment. But taking higher doses of concentrated soy isoflavone extract, 150 mg/day of isoflavones, for 5 years does seem to increase the risk of endometrial hyperplasia.
Regarding Menopausal symptoms: Consuming soy protein 20-60 grams providing 34-76 mg of isoflavones daily seems to modestly decrease the frequency and severity of hot flashes in some menopausal women. Taking concentrated soy isoflavone extracts, providing 35-120 mg of isoflavones daily, seems to have similar beneficial effects. One analysis suggests that soy isoflavone extracts might be more effective in women who have a higher number of hot flashes.
Some research has compared soy isoflavone extracts to conventional estrogen replacement. In one study, a concentrated soy isoflavone extract of genistein 54 mg/day reduced hot flashes by 22% to 29% compared to 53% to 54% with 17beta-estradiol 1mg/day plus norethisterone acetate 0.5 mg/day. Additional preliminary research suggests that taking a soy isoflavone extract providing 60 mg isoflavones twice daily is comparable in efficacy to conjugated estrogens (Premarin) 0.625 daily for reducing menopausal symptoms; however, conjugated estrogens seem to work more quickly. It seems to take up to 2 months for the full effect of soy isoflavones
Eating soy, which has these phytoestrogens, in large quantities seem to have goitregenic properties can affect the thyroid resulting in hypothyroidism in some people. There is also some evidence that soy seems to inhibit thyroid hormone synthesis resulting in increased secretion of TSH in some postmenopausal women. However, this seems to only occur in people with iodine deficiency. In postmenopausal women with normal levels of iodine, taking a soy extract for 6 months does not seem to significantly affect thyroid hormone levels.
Usually bio-identical hormones are made by a compounding pharmacy. You might want to see if you can get what you need through one, so you know you are getting exactly what has been recommended for you. The only product I can find that we have that might suit your needs is this one:
- Bio-Isoflavone by BioGenesis – each capsule has NovaSoy™ (Soy Isoflavones): 50 mg.