Autism, Is HLC Mindlinx 100% casein free, not grown on dairy? Glutamine excitotoxin?
Q: Is HLC Mindlinx 100% casein free, and not grown on dairy? Second, I heard L-Glutamine can become an excitotoxin if not converted to GABA, a process which most people on the autism spectrum could have trouble with, so I am concerned about giving Mindlinx to my son [who is] on the spectrum.
A. Yes, HLC Mindlinx (and all HLC probiotics) are not derived from dairy, thus are 100% free of casein. Second, every study about the level of amino acids on autistic children shows that they are deficient in glutamine. In addition, the vast majority of autistic children have GI tract issues and glutamine is the most important nutrient for the upper part of the GI tract. This surely indicates that glutamine could be a very important supplement for people who are autistic.
The three amino acids glutamic acid (GA), gamma-aminobutyric acid (GABA), and glutamine (GAM) are closely related and all involved in proper brain function. GA is an excitatory neurotransmitter, GABA is an inhibitory neurotransmitter and GAM controls that GA and GABA are in balance. GAM can be converted to both GA and GABA. If adequate vitamin B6 is not present the conversion from GAM to GABA is inhibited and GA could be upregulated. Other factors, which I am not aware of, could potentially upregulate the conversion from GAm to GA, and GAM, therefore, might not be a beneficial supplement for autistic children. However, I would still like to mention that all studies on amino acids levels show that autistic children are deficient in glutamine.
If you have any concerns, you can start your child on HLC Intensive which does not contain any glutamine and use this product for a month or two for intensive gut repair, then switch to HLC Mindlinx.